Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756982 | 0.84 | F2 (0.51) | PLAUELANESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL16757104 | 0.81 | HPGD (0.40) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL5858857 | 0.78 | SMN1; SMN2 (0.41) | PLAUELANESMN1; SMN2MEN1KMT2A | |
| SCHEMBL16756835 | 0.76 | TSHR (0.45) | KMT2AALDH1A1LMNA | |
| SCHEMBL8709450 | 0.75 | ELANE (0.37) | ELANESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4320783 | 0.74 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21186 | 0.73 | NOTUM (0.43) | LMNA | |
| SCHEMBL26184411 | 0.73 | NPC1 (0.38) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7640977 | 0.72 | HSP90AA1 (0.45) | ABL1 | |
| Methane SCHEMBL27916787 | 0.72 | NOTUM (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | disclosed |