Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264255 | 0.81 | RAB9A (0.41) | SMN1; SMN2MEN1KMT2AHPGDELANE | |
| SCHEMBL7635955 | 0.78 | PLAU (0.45) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL31047656 | 0.63 | ALDH1A1 (0.51) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL6280929 | 0.62 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10335889 | 0.62 | — | — | |
| SCHEMBL284242 | 0.61 | EPHX2 (0.66) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL6653589 | 0.60 | SRD5A2 (0.68) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1148445 | 0.60 | SRD5A2 (0.83) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2853873 | 0.60 | HDAC1 (0.64) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10946728 | 0.60 | SRD5A2 (0.83) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105648-B1 | Oligomers substituted by phosphite acid ester, phosphonic acid or carbaborane functions and the corresponding PNA monomers | UGICHEM GMBH (AU) | 2006-09-12 | — | — | US | disclosed |