Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.67 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.67 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.67 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.59 |
| ▸ | HTR3B | O95264 | 2/20 | 0.59 |
| ▸ | HTR3A | P46098 | 2/20 | 0.59 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.59 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179223 | 0.83 | HTR3E (0.61) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL9490171 | 0.81 | TAAR1 (0.60) | TAAR1IDO1AGXT | |
| SCHEMBL7636620 | 0.80 | GRIN2B (0.52) | GRIN2BGRIN1HTR3EHTR3BHTR3A | |
| SCHEMBL3004829 | 0.78 | TAAR1 (0.56) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| SCHEMBL4093147 | 0.78 | GRIN2B (0.65) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL11114919 | 0.77 | GRIN2B (0.50) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| SCHEMBL11488999 | 0.77 | TAAR1 (0.55) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| SCHEMBL15219801 | 0.77 | TAAR1 (0.55) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| SCHEMBL10156019 | 0.76 | GRIN2B (0.49) | GRIN2BGRIN1 | |
| SCHEMBL5243976 | 0.75 | SMN1; SMN2 (0.57) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |