Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | AGXT | P21549 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636634 | 0.80 | GRIN2B (0.67) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| SCHEMBL9490171 | 0.79 | TAAR1 (0.60) | TAAR1IDO1AGXTAOC3MAOB | |
| SCHEMBL7638555 | 0.78 | TAAR1 (0.56) | TAAR1IDO1AGXTPRSS1PRSS2 | |
| SCHEMBL15219801 | 0.78 | TAAR1 (0.55) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| Hydrochloric Acid SCHEMBL7851869 | 0.77 | IDO1 (0.57) | TAAR1IDO1AGXTPRSS1PRSS2 | |
| SCHEMBL3004829 | 0.75 | TAAR1 (0.56) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| SCHEMBL10310205 | 0.74 | ALDH1A1 (0.60) | — | |
| SCHEMBL11488999 | 0.74 | TAAR1 (0.55) | GRIN2BGRIN1TAAR1IDO1AGXT | |
| Hydrochloric Acid SCHEMBL8470380 | 0.73 | IDO1 (0.69) | TAAR1IDO1AGXT | |
| SCHEMBL8061071 | 0.73 | NOS1 (0.70) | TAAR1IDO1AGXTPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |