SCHEMBL7636655

SCHEMBL7636655

CC(C)(C)C1=Cc2ccccc2C1[Zr]C1C(C(C)(C)C)=Cc2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27527194 0.76 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2
Chloromethane SCHEMBL3686216 0.74 LMNA (0.32)
SCHEMBL29959660 0.74 LMNA (0.33)
SCHEMBL688487 0.74 LMNA (0.33)
SCHEMBL28230694 0.74 LMNA (0.33)
Hydrochloric Acid SCHEMBL4089085 0.73 CYP19A1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL4063281 0.73 CYP19A1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL4094226 0.73 CYP19A1 (0.33) CYP19A1CYP11B1CYP11B2
SCHEMBL5387759 0.73
SCHEMBL7025710 0.73 KIF11 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391991-B1 USING COORDINATION POLYMERIZATION CATALYST BASELL TECHNOLOGY COMPANY BV (NL) 2002-05-21 US disclosed
EP-0693506-A2 Process for the preparation of amorphous polymers of propylene SPHERILENE S.p.A. (IT) 1996-01-24 EP disclosed