SCHEMBL7636775

SCHEMBL7636775

O=C(c1ccc(Cl)cc1)C1(O)CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.46
HDAC4 P56524 1/20 0.46
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
GSK3B P49841 1/20 0.44
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HDAC1 Q13547 1/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 2/20 0.40
SRD5A2 P31213 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11303491 0.98 HDAC4 (0.47) HSD11B1HDAC4CES2CES1GSK3B
SCHEMBL6696391 0.84 SRD5A2 (0.39) HDAC4ALOX15TSHRLMNAALDH1A1
SCHEMBL10943813 0.84 CES2 (0.39) HDAC4CES2CES1
SCHEMBL6692915 0.82 SRD5A2 (0.41) ALOX15TSHRLMNAALDH1A1SRD5A2
SCHEMBL10943780 0.82 CES2 (0.41) CES2CES1
SCHEMBL4674963 0.81 CES2 (0.42) CES2CES1GSK3BALOX15TSHR
SCHEMBL4674968 0.81 DRD2 (0.53) CES2CES1GSK3BALOX15TSHR
SCHEMBL27599267 0.81 CES2 (0.45) HSD11B1HDAC4CES2CES1GSK3B
SCHEMBL3677117 0.81 FASN (0.36) HDAC4HDAC1ALDH1A1
SCHEMBL27416408 0.81 CES2 (0.45) HSD11B1CES2CES1TSHRHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369406-B Photocatalytic synthesis method and application of 1-hydroxycyclohexyl phenyl ketone compound 甘肃金盾化工有限责任公司 2021-12-14 CN disclosed
CN-109369406-A A kind of photocatalytic synthesis method of 1- hydroxycyclohexyl phenyl ketone class compound and its application 甘肃金盾化工有限责任公司 2019-02-22 CN disclosed
US-20020022130-A1 UV-curable binder composition for magnetic recording media and photoinitiator mixture EMTEC MAGNETICS GMBH (DE) 2002-02-21 US disclosed
EP-1141952-A1 UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE EMTEC Magnetics GmbH (DE) 2001-10-10 EP disclosed
WO-2000028531-A1 UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE EMTEC MAGNETICS GMBH (DE) 2000-05-18 WO disclosed
EP-0446175-A2 Mixture of photoinitiators CIBA-GEIGY AG (CH) 1991-09-11 EP disclosed