Cumene Hydroperoxide

Cumene Hydroperoxide

SCHEMBL7636780

CC(=O)OOC(C)=O.CC(C)(C)OO.CC(C)(OO)c1ccccc1

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
ALOX15 P16050 1/20 0.68
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
KCNN4 O15554 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cumene Hydroperoxide SCHEMBL874175 0.87 ALDH1A1 (0.91) ALDH1A1ALOX15MAPK1TDP1TSHR
Cumene Hydroperoxide SCHEMBL22579052 0.85 ALDH1A1 (0.86) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL3957342 0.83 MAPK1 (0.68) ALDH1A1ALOX15MAPK1TDP1TSHR
Cumene Hydroperoxide SCHEMBL28089490 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15MAPK1TSHRMAPT
Cumene Hydroperoxide SCHEMBL374888 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15MAPK1TSHRMAPT
Cumene Hydroperoxide SCHEMBL15251 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15MAPK1TSHRMAPT
Cumene Hydroperoxide SCHEMBL28202027 0.80 ALDH1A1 (0.95) ALDH1A1ALOX15MAPK1TSHRMAPT
SCHEMBL11586480 0.79 MAPK1 (0.61) ALDH1A1ALOX15MAPK1TDP1TSHR
Cumene Hydroperoxide SCHEMBL28105735 0.79 ALDH1A1 (0.83) ALDH1A1ALOX15MAPK1TDP1TSHR
Benzoyl Peroxide SCHEMBL8482745 0.79 ALDH1A1 (0.68) ALDH1A1ALOX15MAPK1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718336-B1 Polyurethane low profile additives for polyester-based molding compositions UNION CARBIDE CHEM PLASTIC (US) 2002-09-18 EP disclosed