Cumene Hydroperoxide

Cumene Hydroperoxide

SCHEMBL874175

CC(C)(C)OO.CC(C)(OO)c1ccccc1

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.91
ALOX15 P16050 1/20 0.91
MAPK1 P28482 1/20 0.58
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
KCNN4 O15554 4/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cumene Hydroperoxide SCHEMBL28089490 0.95 ALDH1A1 (1.00) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL374888 0.95 ALDH1A1 (1.00) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL15251 0.95 ALDH1A1 (1.00) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL28202027 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL28105735 0.91 ALDH1A1 (0.83) ALDH1A1ALOX15MAPK1ESR1ESR2
Tert-Butyl Hydroperoxide SCHEMBL20162080 0.88 MAPK1 (0.77) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL27711546 0.88 ALDH1A1 (0.86) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL22579052 0.88 ALDH1A1 (0.86) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL8652869 0.88 ALDH1A1 (0.86) ALDH1A1ALOX15MAPK1ESR1ESR2
Cumene Hydroperoxide SCHEMBL7636780 0.87 ALDH1A1 (0.68) ALDH1A1ALOX15MAPK1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2618929-B1 AN IMPROVED PROCESS FOR THE EPOXIDATION OF FATTY ACIDS, THEIR ESTERS AND MIXTURES THEREOF COUNCIL SCIENT IND RES (IN) 2018-03-14 EP disclosed
EP-2618929-A1 AN IMPROVED PROCESS FOR THE EPOXIDATION OF FATTY ACIDS, THEIR ESTERS AND MIXTURES THEREOF Council of Scientific & Industrial Research (IN) 2013-07-31 EP disclosed
WO-2012038811-A1 AN IMPROVED PROCESS FOR THE EPOXIDATION OF FATTY ACIDS, THEIR ESTERS AND MIXTURES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-03-29 WO disclosed