Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852296 | 0.97 | LMNA (0.41) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL5570835 | 0.97 | LMNA (0.41) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8852311 | 0.97 | LMNA (0.41) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL5387369 | 0.97 | LMNA (0.41) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL5572091 | 0.97 | LMNA (0.41) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL3239590 | 0.95 | LMNA (0.40) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL329400 | 0.95 | LMNA (0.40) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL705813 | 0.95 | LMNA (0.31) | LMNA | |
| SCHEMBL3229747 | 0.92 | LMNA (0.39) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL10701293 | 0.92 | TSHR (0.44) | LMNATSHRTHRBDNM1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628903-B | The method for preparing olefin polymer | 住友化学株式会社 | 2018-02-16 | — | — | CN | disclosed |
| US-6376628-B1 | USING COORDINATION POLYMERIZATION CATALYST | GRAND POLYMER CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-0959083-A1 | Process for polymerization of alpha-olefin and alpha-olefin polymer | Grand Polymer Co., Ltd. (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5594079-A | COORDINATION CATALYST CONTAINING BORON, STEREOREGULAR POLYPROPYLENE | TOSOH CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0582278-A2 | Method for producing a polyolefin | TOSOH CORPORATION (JP) | 1994-02-09 | — | — | EP | disclosed |