Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894950 | 0.81 | CYP3A4 (0.53) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7636297 | 0.77 | ALDH1A1 (0.33) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7631116 | 0.73 | CYP1A2 (0.31) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3419436 | 0.73 | CYP1A2 (0.66) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10343906 | 0.72 | S100B (0.46) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8863601 | 0.71 | CYP3A4 (0.48) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4765911 | 0.71 | ALDH1A1 (0.37) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29385647 | 0.70 | ALDH1A1 (0.49) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4897902 | 0.70 | ALDH1A1 (0.49) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8863620 | 0.70 | HSD17B10 (0.47) | HSD17B10CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |