Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637540 | 1.00 | KMT2A (0.58) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7632815 | 0.85 | MEN1 (0.56) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7632818 | 0.85 | MEN1 (0.56) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637533 | 0.83 | MEN1 (0.72) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637536 | 0.83 | MEN1 (0.72) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637808 | 0.80 | ATM (0.66) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637812 | 0.80 | ATM (0.66) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL3679074 | 0.80 | SMN1; SMN2 (0.57) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL3679075 | 0.80 | SMN1; SMN2 (0.57) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL5270097 | 0.80 | LMNA (0.79) | KMT2AMEN1CYP2D6CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | claimed |
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | disclosed |