Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637536 | 1.00 | MEN1 (0.72) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL9097239 | 0.83 | LMNA (0.60) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637540 | 0.83 | KMT2A (0.58) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637544 | 0.83 | KMT2A (0.58) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL11446037 | 0.82 | MEN1 (0.58) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL11696689 | 0.81 | MEN1 (0.60) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL2168291 | 0.80 | CASR (0.67) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL4074646 | 0.80 | CASR (0.67) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL27535379 | 0.80 | CASR (0.67) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7637808 | 0.79 | ATM (0.66) | MEN1KMT2ACYP2D6CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | claimed |
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | disclosed |