Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071762 | 1.00 | LMNA (0.47) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL1071759 | 1.00 | LMNA (0.47) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL808887 | 0.86 | LMNA (0.47) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL808888 | 0.86 | LMNA (0.47) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL3683341 | 0.83 | LMNA (0.66) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL6439369 | 0.83 | LMNA (0.66) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL10989214 | 0.83 | LMNA (0.66) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL294747 | 0.83 | LMNA (0.66) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL2219671 | 0.83 | LMNA (0.66) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL808908 | 0.81 | LMNA (0.46) | LMNATSHRCYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414181-B1 | REACTING CYCLOPROPANECARBALDEHYDE COMPOUND WITH DICARBOXYLATE COMPOUND IN PRESENCE OF AT LEAST ONE SECONDARY AMINE CHOOSEN FROM PIPERIDINE, MORPHOLINE, PYRROLIDINE, DIETHYLAMINE AND N-METHYLETHANOLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-07-02 | — | — | US | disclosed |