Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.64 |
| ▸ | THRA | P10827 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932269 | 0.97 | ALDH1A1 (0.61) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL15535898 | 0.88 | THRA (0.63) | TP53TSHRTHRATHRBALDH1A1 | |
| SCHEMBL6539277 | 0.86 | TP53 (0.60) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL10460818 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL578734 | 0.83 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL15172203 | 0.83 | TP53 (0.65) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL12190754 | 0.82 | TP53 (0.74) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL9388919 | 0.82 | ALDH1A1 (0.66) | PLA2G4BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17203727 | 0.82 | TP53 (0.74) | TP53TSHRPLA2G4BTHRATHRB | |
| SCHEMBL13221522 | 0.82 | TSHR (0.55) | TP53TSHRPLA2G4BTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1004304-A1 | COMPOSITION CONTAINING ASCORBIC ACID | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |