SCHEMBL7637853

SCHEMBL7637853

O=C(O)c1ccnc(-c2cc(C(=O)O)cc(-c3cc(C(=O)O)cc(-c4cc(C(=O)O)ccn4)n3)n2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5C P41229 9/20 0.68
KDM4C Q9H3R0 8/20 0.68
KDM4A O75164 7/20 0.68
KDM4E B2RXH2 6/20 0.68
KDM2A Q9Y2K7 5/20 0.68
KDM3A Q9Y4C1 5/20 0.68
KDM6B O15054 4/20 0.68
P4HA1 P13674 1/20 0.66
KDM5B Q9UGL1 8/20 0.63
KDM4B O94953 4/20 0.63
JMJD6 Q6NYC1 1/20 0.60
KDM5A P29375 4/20 0.57
TET3 O43151 1/20 0.57
BBOX1 O75936 1/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPT P10636 1/20 0.57
ASPH Q12797 1/20 0.57
KDM4D Q6B0I6 1/20 0.57
TET2 Q6N021 1/20 0.57
ALKBH5 Q6P6C2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29699785 1.00 KDM5C (0.68) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL449879 1.00 KDM5C (0.68) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL30892481 0.98 KDM5C (0.66) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL29407015 0.92 KDM4C (0.78) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL70700 0.92 KDM4C (0.78) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL16976900 0.91 KDM5C (0.73) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL18677557 0.90 KDM5C (0.57) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL863220 0.90 KDM5C (0.87) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL8572040 0.90 KDM5B (0.60) KDM5CKDM4CKDM4AKDM4EKDM2A
SCHEMBL25273097 0.90 KDM4C (0.75) KDM5CKDM4CKDM4AKDM4EKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6437130-B1 FOR USE IN DYE SENSITIZING TYPE SOLAR BATTERY AISIN SEIKI KABUSHIKI KAISHA (JP) 2002-08-20 US claimed
US-20020082422-A1 PYRIDINE DERIVATIVE AND ITS COMPLEX AISIN SEIKI KABUSHIKI KAISHA (JP) 2002-06-27 US claimed
US-6437130-B1 FOR USE IN DYE SENSITIZING TYPE SOLAR BATTERY AISIN SEIKI KABUSHIKI KAISHA (JP) 2002-08-20 US disclosed
US-20020082422-A1 PYRIDINE DERIVATIVE AND ITS COMPLEX AISIN SEIKI KABUSHIKI KAISHA (JP) 2002-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082422-A1 PYRIDINE DERIVATIVE AND ITS COMPLEX CBR1, MT-CO1, CBR3 KDM5C 3343/4885KDM4C 905/4885KDM4A 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.