SCHEMBL863220

SCHEMBL863220

O=C(O)c1ccnc(-c2cc(C(=O)O)cc(-c3ccccn3)n2)c1

nearest known ligand 0.87

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM5C P41229 8/20 0.87
KDM4C Q9H3R0 7/20 0.87
KDM4A O75164 6/20 0.87
KDM2A Q9Y2K7 4/20 0.87
KDM3A Q9Y4C1 4/20 0.87
KDM4E B2RXH2 4/20 0.87
KDM6B O15054 3/20 0.87
P4HA1 P13674 1/20 0.59
KDM5B Q9UGL1 7/20 0.54
KDM4B O94953 4/20 0.54
PIN1 Q13526 1/20 0.53
JMJD6 Q6NYC1 1/20 0.51
KDM5A P29375 3/20 0.51
CSNK2A2 P19784 1/20 0.50
CSNK2B P67870 1/20 0.50
CCR1 P32246 1/20 0.50
CCR5 P51681 1/20 0.50
CCR8 P51685 1/20 0.50
METAP1 P53582 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000745 0.94 KDM5C (0.87) KDM5CKDM4CKDM4AKDM2AKDM3A
SCHEMBL29766771 0.94 KDM5C (0.87) KDM5CKDM4CKDM4AKDM2AKDM3A
SCHEMBL913277 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM2AKDM3A
SCHEMBL29562841 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM2AKDM3A
Dipyridyl SCHEMBL21551506 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM2AKDM3A
Dipyridyl SCHEMBL3941503 0.93 KDM4C (1.00) KDM5CKDM4CKDM4AKDM2AKDM3A
SCHEMBL863317 0.93 KDM4E (0.74) KDM5CKDM4CKDM4AKDM2AKDM3A
SCHEMBL29904774 0.93 KDM4E (0.74) KDM5CKDM4CKDM4AKDM2AKDM3A
SCHEMBL16976900 0.92 KDM5C (0.73) KDM5CKDM4CKDM4AKDM2AKDM3A
Dipyridyl SCHEMBL3954422 0.92 KDM4C (0.96) KDM5CKDM4CKDM4AKDM2AKDM3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8759521-B2 Panchromatic photosensitizers and dye-sensitized solar cell using the same NATIONAL TSING HUA UNIVERSITY (TW) 2014-06-24 US disclosed
US-8759521-B2 Panchromatic photosensitizers and dye-sensitized solar cell using the same NATIONAL TSING HUA UNIVERSITY (TW) 2014-06-24 US disclosed
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
US-20120111410-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2012-05-10 US disclosed
US-20120111410-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2012-05-10 US disclosed
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS NATIONAL TSING HUA UNIVERSITY (TW) 2012-03-29 US disclosed
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS NATIONAL TSING HUA UNIVERSITY (TW) 2012-03-29 US disclosed
US-20110155238-A1 PYRIDINE TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE SHARP KABUSHIKI KAISHA (JP) 2011-06-30 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
EP-2275494-A1 PYRIDINE-TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE Sharp Kabushiki Kaisha (JP) 2011-01-19 EP disclosed
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-14 US disclosed
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120111410-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME MLX, PRXL2A, MSL1 KDM5C 917/4885KDM4C 724/4885KDM4A 770/4885
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS RUVBL2, RUVBL1, CCNL2 KDM5C 3148/4885KDM4C 3048/4885KDM4A 3412/4885
US-20110155238-A1 PYRIDINE TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE CD4, AP1M1, CRY1 KDM5C 605/4885KDM4C 230/4885KDM4A 301/4885
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME MLX, PRXL2A, MSL1 KDM5C 907/4885KDM4C 733/4885KDM4A 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.