SCHEMBL7638458

SCHEMBL7638458

C=C(C)COCC[Si](C)(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102499 0.88 CES2 (0.31)
SCHEMBL7701977 0.87 HSD17B10 (0.31) HSD17B10TDP1
SCHEMBL9805440 0.86 CES2 (0.33)
SCHEMBL674775 0.84 HSD17B10 (0.32) HSD17B10TDP1
SCHEMBL9805464 0.84 CES2 (0.36)
SCHEMBL5680550 0.82
SCHEMBL692373 0.79 CES2 (0.31)
SCHEMBL7252713 0.78
SCHEMBL8962563 0.78 CES2 (0.33)
SCHEMBL9805418 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP claimed
US-6399212-B1 COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE NIPPON SHEET GLASS CO., LTD. (JP) 2002-06-04 US disclosed
EP-1094090-A2 Silicon dioxide-coated polyolefin resin and process for its production NIPPON SHEET GLASS CO. LTD. (JP) 2001-04-25 EP disclosed
US-5051486-A Comb like polymers containing siloxane groups with polyoxyalkylene groups NIPPON OIL CO., LTD. (JP) 1991-09-24 US disclosed
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP disclosed