Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18245148 | 0.84 | THRB (0.41) | THRB | |
| SCHEMBL28212362 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL7638470 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL4924486 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL8380164 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL5365862 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL5374510 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL1019945 | 0.83 | THRB (0.52) | THRB | |
| SCHEMBL18192005 | 0.81 | THRB (0.37) | THRB | |
| SCHEMBL6892577 | 0.80 | THRB (0.50) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468502-B1 | PARAMAGNETIC MACROMOLECULES WITH HIGHER PROTON RELAXIVITY; LOWER DOSAGE AND INCREASED SIGNAL INTENSITY; DETECTING VASCULAR DISEASES; DIFFERENTIATING TISSUE BLOOD SUPPLY LEVELS; DISTINGUISHING MYOCARDIAL INFARCTION FROM ISCHEMIA | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |