Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374510 | 1.00 | THRB (0.52) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL5365862 | 1.00 | THRB (0.52) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL4924486 | 1.00 | THRB (0.52) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL1019945 | 1.00 | THRB (0.52) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL8380164 | 1.00 | THRB (0.52) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL28212362 | 1.00 | THRB (0.52) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL6892577 | 0.97 | THRB (0.50) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL7630035 | 0.97 | THRB (0.48) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL9218463 | 0.94 | THRB (0.48) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL15012282 | 0.94 | THRB (0.48) | THRBLMNACA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468502-B1 | PARAMAGNETIC MACROMOLECULES WITH HIGHER PROTON RELAXIVITY; LOWER DOSAGE AND INCREASED SIGNAL INTENSITY; DETECTING VASCULAR DISEASES; DIFFERENTIATING TISSUE BLOOD SUPPLY LEVELS; DISTINGUISHING MYOCARDIAL INFARCTION FROM ISCHEMIA | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |