Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892452 | 1.00 | THRB (0.48) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL28015789 | 1.00 | THRB (0.48) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL15012282 | 1.00 | THRB (0.48) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL3027405 | 0.97 | THRB (0.43) | THRBLMNA | |
| SCHEMBL7638470 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL5374510 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL4924486 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL5365862 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL1019945 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 | |
| SCHEMBL8380164 | 0.94 | THRB (0.52) | THRBLMNACA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552303-B1 | PROCESS FOR PRODUCTION OF POLYFLUOROOLEFINS | DU PONT (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5276221-A | Useful as cleaning agents, solvents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0552303-A1 | PROCESS FOR PRODUCTION OF POLYFLUOROOLEFINS. | DU PONT (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5220082-A | Cleaning agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-15 | — | — | US | disclosed |
| US-5162594-A | Process for production of polyfluoroolefins | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992006942-A1 | PROCESS FOR PRODUCTION OF POLYFLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-30 | — | — | WO | disclosed |