Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638479 | 1.00 | CHRNB2 (0.43) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8926511 | 0.86 | ALDH1A1 (0.43) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2755020 | 0.86 | ALDH1A1 (0.43) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7639459 | 0.85 | ALDH1A1 (0.41) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7633907 | 0.85 | CHRNB2 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7633900 | 0.85 | CHRNB2 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7639463 | 0.85 | ALDH1A1 (0.41) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9246511 | 0.85 | CHRNB2 (0.36) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7643537 | 0.85 | CHRNB2 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7643543 | 0.85 | CHRNB2 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140350-A | APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | claimed |
| CN-1044071-C | Insecticidal agents | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1999-07-14 | — | — | CN | claimed |
| US-5547965-A | TREATMENT AND PREVENTION OF SENILE, PRESENILE, AND ALZHEIMER'S DEMENTIA, AND DEPRESSION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-20 | — | — | US | claimed |
| EP-0375907-B1 | Insecticidally active nitro compounds | BAYER AGROCHEM KK (JP) | 1996-01-03 | — | — | EP | claimed |
| EP-0679397-A2 | Use of substituted amines for the treatment of cerebral insufficiencies | BAYER AG (DE) | 1995-11-02 | — | — | EP | claimed |
| US-5166164-A | Nontoxic to mammals, fish, and crustaceans; nonphytotoxic | AGRO-KANESHO CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| US-5051434-A | Pyridyl, thiazolyl, thiadiazolyl, pyrimidinyl or isooxazolyl groups | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-09-24 | — | — | US | claimed |
| CN-1045333-A | Insecticide | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1990-09-19 | — | — | CN | claimed |
| EP-0375907-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-07-04 | — | — | EP | claimed |
| US-9919979-B2 | Fertilizer-compatible composition | BAYER CROPSCIENCE LP (US) | 2018-03-20 | — | — | US | disclosed |
| US-9662309-B2 | Anti-demodicosis agent | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-30 | — | — | US | disclosed |
| US-8993483-B2 | Combination of active substances with insecticidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8841294-B2 | Active ingredient combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-09-23 | — | — | US | disclosed |
| US-8728507-B2 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-5051434-A | Pyridyl, thiazolyl, thiadiazolyl, pyrimidinyl or isooxazolyl groups | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-09-24 | — | — | US | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-1045333-A | Insecticide | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1990-09-19 | — | — | CN | disclosed |
| EP-0376279-A2 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0375907-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-07-04 | — | — | EP | disclosed |