⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830748 | 0.83 | POLB (1.00) | — | |
| SCHEMBL3159562 | 0.80 | POLB (0.60) | — | |
| SCHEMBL7962385 | 0.80 | POLB (0.93) | — | |
| SCHEMBL1323731 | 0.78 | POLB (0.75) | — | |
| SCHEMBL10938020 | 0.78 | POLB (0.75) | — | |
| SCHEMBL18710961 | 0.77 | POLB (0.72) | — | |
| SCHEMBL4592216 | 0.76 | POLB (0.55) | — | |
| SCHEMBL10773262 | 0.75 | — | — | |
| SCHEMBL1195000 | 0.75 | FAAH (0.58) | — | |
| SCHEMBL5141666 | 0.73 | FAAH (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-113905607-B | Heterocyclic compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2022-12-27 | — | — | CN | disclosed |
| EP-4081515-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | Blueprint Medicines Corporation (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135642-A | Inhibitors of mutant forms of EGFR | 缆图药品公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-113905607-A | Heterocyclic compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2022-01-07 | — | — | CN | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| WO-2021133809-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | BLUEPRINT MEDICINES CORPORATION (US) | 2021-07-01 | — | — | WO | disclosed |
| CN-108689942-A | Nitrogenous dicyclic compound and its preparation method and application | 广东东阳光药业有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-20070232649-A1 | Heteroaryl Sulfones and Sulfonamides and Therapeutic Uses Thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2007-10-04 | — | — | US | disclosed |
| CN-1262881-C | Potch processing compound, processing apparatus and method for processing silver coloured camera | FUJI PHOTO FILM CO LTD (JP) | 2006-07-05 | — | — | CN | disclosed |
| CN-1407400-A | Potch processing compound, processing apparatus and method for processing silver coloured camera | FUJI PHOTO FILM CO LTD (JP) | 2003-04-02 | — | — | CN | disclosed |
| US-4051129-A | REACTION OF BENZYLIDENIMINO GROUP WITH HYDRAZINE, AMIDATION | SANKYO COMPANY LIMITED (JA) | 1977-09-27 | — | — | US | disclosed |
| US-3960853-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3960852-A | BACTERICIDES | SMITHKLINE BECKMAN CORPORATION | 1976-06-01 | — | — | US | disclosed |
| US-3960855-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3948905-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3939266-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |