Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206354 | 0.98 | TSHR (0.57) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL1283310 | 0.92 | TSHR (0.69) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5706067 | 0.89 | TSHR (0.65) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL4391361 | 0.87 | TSHR (0.67) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL4397337 | 0.86 | TSHR (0.61) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL2842657 | 0.86 | TSHR (0.61) | TSHRALDH1A1HSD17B10MAPTL3MBTL1 | |
| SCHEMBL1282822 | 0.85 | TSHR (0.59) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5706118 | 0.85 | TSHR (0.59) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL2910803 | 0.84 | KDM4E (0.63) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL5706247 | 0.84 | SLC6A3 (0.59) | TSHRALDH1A1HSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410777-B1 | HALOGEN-FREE | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6300459-B1 | TRANSESTERIFYING AROMATIC POLYCARBONATE AND ACTIVE-HYDROGEN COMPOUND UNDER REDUCED PRESSURE FOLLOWED BY REACTION WITH SPECIFIED SALICYLIC ESTER DERIVATIVE | TEIJIN LIMITED (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0982340-A1 | PROCESS FOR PRODUCING AROMATIC POLYCARBONATE | TEIJIN LIMITED (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0980861-A1 | SALICYLIC ESTER DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2000-02-23 | — | — | EP | disclosed |