SCHEMBL1282822

SCHEMBL1282822

CCOC(=O)c1ccccc1OC(=O)Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.59
ALDH1A1 P00352 5/20 0.51
HSD17B10 Q99714 4/20 0.51
MAPT P10636 4/20 0.51
MAPK10 P53779 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 2/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 4/20 0.47
CYP1A2 P05177 3/20 0.46
CYP2C9 P11712 3/20 0.46
CYP2C19 P33261 2/20 0.46
LMNA P02545 1/20 0.45
SLC6A3 Q01959 1/20 0.45
MEN1 O00255 2/20 0.45
USP2 O75604 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1283310 0.92 TSHR (0.69) TSHRALDH1A1HSD17B10MAPTMAPK10
SCHEMBL4397335 0.91 TSHR (0.56) TSHRALDH1A1HSD17B10MAPTMAPK10
SCHEMBL5705989 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10MAPTSMN1; SMN2
SCHEMBL5706220 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10SMN1; SMN2KDM4E
SCHEMBL5706120 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10MAPTMAPK10
SCHEMBL5706235 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10MAPTMAPK10
SCHEMBL5706067 0.89 TSHR (0.65) TSHRALDH1A1HSD17B10MAPTMAPK10
SCHEMBL1283321 0.88 ALDH1A1 (0.61) TSHRALDH1A1HSD17B10MAPTSMN1; SMN2
SCHEMBL4385296 0.88 HSD17B10 (0.54) TSHRALDH1A1HSD17B10MAPTSMN1; SMN2
SCHEMBL4391361 0.87 TSHR (0.67) TSHRALDH1A1HSD17B10MAPTMAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US claimed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US claimed
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
US-12365775-B2 Process for partial colouring of plastic parts using solid colourants in colour- carrier layers COVESTRO DEUTSCHLAND AG (DE) 2025-07-22 US disclosed
US-20250205963-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-06-26 US disclosed
EP-4549163-A2 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2025-05-07 EP disclosed
WO-2025088996-A1 FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE OF SAME 信越化学工業株式会社 2025-05-01 WO disclosed
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20250091332-A1 FILM STRUCTURE SUITABLE FOR RAPID LAMINATION COVESTRO DEUTSCHLAND AG (DE) 2025-03-20 US disclosed
EP-3055344-B1 POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP disclosed
EP-1114841-A1 PROCESS FOR PRODUCING POLYARYLATE TEIJIN LIMITED (JP) 2001-07-11 EP disclosed
EP-1019237-A1 TWINSCREW EXTRUDER, METHOD OF MAKING AROMATIC POLYCARBONATE USING A TWINSCREW EXTRUDER, AND METHOD OF REMOVING VOLATILES FROM AN AROMATIC POLYCARBONATE MELT TEIJIN LIMITED (JP) 2000-07-19 EP disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
WO-2000007799-A1 TWIN SCREW EXTRUDER, METHOD OF MAKING AROMATIC POLYCARBONATE USING A TWIN SCREW EXTRUDER, AND METHOD OF REMOVING VOLATILES FROM AN AROMATIC POLYCARBONATE MELT TEIJIN LIMITED (JP) 2000-02-17 WO disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL TSHR 4367/4885ALDH1A1 4181/4885HSD17B10 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.