Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.60 |
| ▸ | RHOA | P61586 | 1/20 | 0.49 |
| ▸ | FGF1 | P05230 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407421 | 0.81 | SNCA (0.62) | CASP6SNCANSD2DUSP3PTPN5 | |
| SCHEMBL631327 | 0.81 | SNCA (0.62) | CASP6SNCANSD2DUSP3PTPN5 | |
| SCHEMBL31720743 | 0.81 | SNCA (0.62) | CASP6SNCANSD2DUSP3PTPN5 | |
| SCHEMBL7046526 | 0.81 | CASP6 (0.62) | CASP6RHOASNCANSD2DUSP3 | |
| SCHEMBL31614400 | 0.80 | SNCA (0.63) | CASP6RHOAFGF1SNCANSD2 | |
| SCHEMBL291102 | 0.80 | SNCA (0.63) | CASP6RHOAFGF1SNCANSD2 | |
| SCHEMBL7194445 | 0.80 | SNCA (0.51) | CASP6RHOASNCANSD2DUSP3 | |
| SCHEMBL9627398 | 0.78 | CASP6 (0.58) | CASP6RHOAFGF1SNCAPRMT1 | |
| SCHEMBL7194449 | 0.77 | SNCA (0.51) | CASP6RHOASNCANSD2DUSP3 | |
| SCHEMBL9627393 | 0.77 | CASP6 (0.60) | CASP6RHOAFGF1SNCAPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395556-B1 | DETECTING THE PRESENCE/CONCENTRATION OF AN ANALYTE; USING FLUORESCENT REFERENCE MOLECULES AND EXPOSE A SAMPLE TO THE REFERENCE MOLECULE; MEASURE INTENSITY CHANGES BY DETERMINING POLARIZATION AXES AFTER EXPOSURE TO A RADIATION SOURCE | LAKOWICZ JOSEPH R (US) | 2002-05-28 | — | — | US | disclosed |