Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.62 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720743 | 1.00 | SNCA (0.62) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL29407421 | 1.00 | SNCA (0.62) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL7036230 | 0.83 | PRMT1 (0.51) | CA2CA1CA12CA9PRMT1 | |
| SCHEMBL15444335 | 0.82 | MAPT (0.59) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6381706 | 0.82 | PRMT1 (0.50) | CA2CA1CA12CA9PRMT1 | |
| SCHEMBL4349757 | 0.82 | SNCA (0.83) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL7639620 | 0.81 | CASP6 (0.60) | SNCACASP6NSD2DUSP3PTPN5 | |
| SCHEMBL7213213 | 0.81 | PRMT1 (0.49) | CA2CA1CA12CA9PRMT1 | |
| Water SCHEMBL5146224 | 0.81 | PRMT1 (0.49) | CA2CA1CA12CA9PRMT1 | |
| SCHEMBL29668447 | 0.77 | SNCA (1.00) | SNCACASP6NSD2DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146366-A1 | ASSAYS RELATING TO BIOMIMETIC MEMBRANES AND THEIR USES | AQUAPORIN A/S (DK) | 2010-12-23 | — | — | WO | claimed |
| US-20080269317-A1 | Compounds for Covalent Binding to MD-2 and Effect on the Immune Response | KEMIJSKI INSTITUT (SI) | 2008-10-30 | — | — | US | claimed |
| EP-1335984-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) | Biosensor APS (DK) | 2003-08-20 | — | — | EP | claimed |
| US-20020142347-A1 | Biosensor | BIOSENSOR APS (DK) | 2002-10-03 | — | — | US | claimed |
| WO-2002061096-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) | BIOSENSOR APS (DK) | 2002-08-08 | — | — | WO | claimed |
| WO-2021150578-A1 | FLUORESCENTLY-LABELED F-ACTIN PROTEIN BIOSENSORS AND METHODS OF HIGH-THROUGHPUT DRUG DISCOVERY | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-07-29 | — | — | WO | disclosed |
| EP-2442894-B1 | BIOMIMETRIC MEMBRANES AND USES THEREOF | AQUAPORIN AS (DK) | 2018-04-11 | — | — | EP | disclosed |
| EP-2651542-B1 | A LIQUID MEMBRANE SUITABLE FOR WATER EXTRACTION | AQUAPORIN AS (DK) | 2017-02-15 | — | — | EP | disclosed |
| US-20160282357-A1 | METHODS AND COMPOSITIONS RELATED TO NUCLEIC ACID BINDING ASSAYS | Nubad, LLC | 2016-09-29 | — | — | US | disclosed |
| US-9410186-B2 | Methods and compositions related to nucleic acid binding assays | NUBAD LLC (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2977097-A1 | BIOMETRIC MEMBRANES WITH VESICLES COMPRISIN AQUAPORIN AND USES THEREOF | Aquaporin A/S (DK) | 2016-01-27 | — | — | EP | disclosed |
| US-20150360183-A1 | BIOMIMETIC MEMBRANES AND USES THEREOF | AQUAPORIN A/S (DK) | 2015-12-17 | — | — | US | disclosed |
| WO-2002061096-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) | BIOSENSOR APS (DK) | 2002-08-08 | — | — | WO | disclosed |
| US-20020051996-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | AMYLIN PHARMACEUTICALS, INC. | 2002-05-02 | — | — | US | disclosed |
| EP-0906333-B1 | SUBSTRATES AND INHIBITORS OF PROTEOLYTIC ENZYMES | MEDIVIR UK LTD (GB) | 2001-07-25 | — | — | EP | disclosed |
| EP-1098658-A1 | ENGINEERED PROTEINS FOR ANALYTE SENSING | University of Maryland, Baltimore (US) | 2001-05-16 | — | — | EP | disclosed |
| US-6197534-B1 | Engineered proteins for analyte sensing | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-03-06 | — | — | US | disclosed |
| EP-1009757-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | Gryphon Sciences (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000003727-A1 | ENGINEERED PROTEINS FOR ANALYTE SENSING | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999011655-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | GRYPHON SCIENCES (US) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020051996-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | CXCL12, CCL2, SDF4 | SNCA 3658/4885CASP6 4728/4885NSD2 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.