Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27130747 | 0.91 | TSHR (0.46) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7636561 | 0.84 | TSHR (0.42) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3210423 | 0.82 | THRB (0.56) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9296328 | 0.81 | THRB (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28053779 | 0.81 | TSHR (0.42) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL24963 | 0.81 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3028011 | 0.80 | THRB (0.61) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL16584126 | 0.80 | THRB (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL4593744 | 0.80 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3136846 | 0.80 | TSHR (0.41) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399212-B1 | COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE | NIPPON SHEET GLASS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1094090-A2 | Silicon dioxide-coated polyolefin resin and process for its production | NIPPON SHEET GLASS CO. LTD. (JP) | 2001-04-25 | — | — | EP | disclosed |