SCHEMBL3136846

SCHEMBL3136846

C=C(C)C(=O)OC(C)CCO[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2540758 0.84 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL24963 0.83 TSHR (0.52) TSHRALDH1A1THRB
SCHEMBL3411386 0.83 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL4593744 0.81 THRB (0.52) TSHRALDH1A1THRB
SCHEMBL29196045 0.81 TSHR (0.44) TSHRALDH1A1THRB
Propane SCHEMBL8440363 0.80 THRB (0.50) TSHRALDH1A1THRB
SCHEMBL14394272 0.80 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL13154905 0.80 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL7640083 0.80 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL2638252 0.79 TSHR (0.39) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100003419-A1 METHOD OF PRODUCING A SHAPED ARTICLE HAVING EXCELLENT BARRIER PROPERTIES KURARAY CO., LTD. (JP) 2010-01-07 US disclosed
US-20100003437-A1 METHOD OF PRODUCING A SHAPED ARTICLE HAVING EXCELLENT BARRIER PROPERTIES KURARAY CO., LTD. (JP) 2010-01-07 US disclosed
EP-1166892-B1 A method of producing a shaped article having excellent barrier properties KURARAY CO (JP) 2006-09-27 EP disclosed
US-20050233086-A1 Method of producing a shaped article having excellent barrier properties KURARAY CO., LTD (JP) 2005-10-20 US disclosed
EP-1245381-B1 Fuel container having excellent gasoline barrier properties KURARAY CO (JP) 2005-08-03 EP disclosed
US-6884482-B2 Fuel container having excellent gasoline barrier properties KURARAY CO., LTD. (JP) 2005-04-26 US disclosed
US-20040076780-A1 Method of producing a shaped article having excellent barrier properties KURARAY CO. LTD (JP) 2004-04-22 US disclosed
US-20020176955-A1 Fuel container having excellent gasoline barrier properties EVAL COMPANY OF AMERICA 2002-11-28 US disclosed
US-20020172788-A1 Method of producing a shaped article having excellent barrier properties KURARAY CO., LTD. (JP) 2002-11-21 US disclosed
EP-1245381-A1 Fuel container having excellent gasoline barrier properties Kuraray Co., Ltd. (JP) 2002-10-02 EP disclosed
EP-1166892-A2 A method of producing a shaped article having excellent barrier properties Kuraray Co., Ltd. (JP) 2002-01-02 EP disclosed
US-5281449-A Coating and curing then development with alkali KANSAI PAINT COMPANY, LIMITED (JP) 1994-01-25 US disclosed