SCHEMBL7640187

SCHEMBL7640187

O=C(O)C=CC=C(CC1CCCO1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 4/20 0.36
POLB P06746 1/20 0.36
USP2 O75604 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TP53 P04637 1/20 0.35
ALOX12 P18054 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17335817 0.82
SCHEMBL7251492 0.79 ALDH1A1 (0.42) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL8171699 0.79 HPGD (0.44) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL3454658 0.79 ALDH1A1 (0.42) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL3454655 0.79 ALDH1A1 (0.42) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL1275343 0.74 MAPT (0.39) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL1275344 0.74 MAPT (0.39) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL8418119 0.71 ALDH1A1 (0.46) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL8416348 0.71 ALDH1A1 (0.46) KDM4EALDH1A1LMNAHPGDPOLB
SCHEMBL2791054 0.71 LMNA (0.46) KDM4EALDH1A1LMNAHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6489377-B1 DISSOLVING MATRICES COMPRISING POLYMERS AND IMMISCIBLE ALIPHATIC HYDROCARBONS IN SOLUTIONS CONTAINING OLIGOMERS, THINNERS AND PHOTOINITIATORS, THEN HARDENING USING ULTRAVIOLET RADIATION; SHADES FOR WINDOWS FRAUNHOGER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2002-12-03 US disclosed
EP-1095080-A1 METHOD FOR PRODUCING THERMOTROPIC CASTING RESIN SYSTEMS AND UTILIZATION THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2001-05-02 EP disclosed
WO-1999064488-A1 METHOD FOR PRODUCING THERMOTROPIC CASTING RESIN SYSTEMS AND UTILIZATION THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 1999-12-16 WO disclosed