Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 2/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | WEE1 | P30291 | 3/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056 | 0.92 | KIT (0.45) | KITPDGFRAFGFR3NQO2NQO1 | |
| SCHEMBL29371790 | 0.92 | KIT (0.45) | KITPDGFRAFGFR3NQO2NQO1 | |
| SCHEMBL29435144 | 0.92 | KIT (0.45) | KITPDGFRAFGFR3NQO2NQO1 | |
| Hydrochloric Acid SCHEMBL5953239 | 0.91 | KIT (0.45) | KITPDGFRAFGFR3NQO2NQO1 | |
| Hydrochloric Acid SCHEMBL29613355 | 0.91 | KIT (0.45) | KITPDGFRAFGFR3NQO2NQO1 | |
| SCHEMBL8542307 | 0.88 | KIT (0.48) | KITPDGFRAFGFR3NQO2NQO1 | |
| Dimethylamine SCHEMBL7640258 | 0.87 | KIT (0.43) | KITPDGFRAFGFR3HPGDKDM4E | |
| SCHEMBL27118310 | 0.83 | POLB (0.46) | KITPDGFRAFGFR3HPGDKDM4E | |
| SCHEMBL24277208 | 0.83 | KIT (0.40) | KITPDGFRAFGFR3ALDH1A1BCHE | |
| SCHEMBL8543762 | 0.83 | KIT (0.42) | KITPDGFRAFGFR3HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895995-B1 | Bis pyrido[4,3-b]carbazole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-06-05 | — | — | EP | disclosed |
| EP-0895995-A1 | Bis pyrido[4,3-b]carbazole compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-10 | — | — | EP | disclosed |