Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8546032 | 0.91 | KIT (0.44) | KITPDGFRAFGFR3BCHEACHE | |
| Dimethylamine SCHEMBL8548130 | 0.88 | KIT (0.44) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL7640244 | 0.87 | KIT (0.45) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL8543762 | 0.84 | KIT (0.42) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL8545625 | 0.83 | KIT (0.42) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL8545879 | 0.82 | GAA (0.47) | KITPDGFRAFGFR3GAAKDM4E | |
| SCHEMBL8390257 | 0.82 | KIT (0.42) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL29860013 | 0.82 | KIT (0.41) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL29435144 | 0.82 | KIT (0.45) | KITPDGFRAFGFR3KDM4EALDH1A1 | |
| SCHEMBL29371790 | 0.82 | KIT (0.45) | KITPDGFRAFGFR3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895995-B1 | Bis pyrido[4,3-b]carbazole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-06-05 | — | — | EP | disclosed |
| EP-0895995-A1 | Bis pyrido[4,3-b]carbazole compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-10 | — | — | EP | disclosed |