Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600840 | 0.93 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1ACACBSMN1; SMN2 | |
| SCHEMBL7633208 | 0.93 | ITGB3 (0.45) | ITGB3ITGA2BALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL7631925 | 0.91 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1F10 | |
| SCHEMBL7639718 | 0.91 | ITGB3 (0.39) | ITGB3ITGA2BALDH1A1TSHRSIGMAR1 | |
| SCHEMBL7633507 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL7640427 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1SIGMAR1F10 | |
| SCHEMBL6600429 | 0.88 | GRM2 (0.40) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7637805 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL7640396 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BSIGMAR1ACACBF10 | |
| SCHEMBL7639664 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BSIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |