SCHEMBL7640418

SCHEMBL7640418

CCCCc1ccc(Cl)c(CCCC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.47
SIGMAR1 Q99720 3/20 0.46
HPGD P15428 2/20 0.42
NPC1 O15118 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
GLA P06280 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
CTRC Q99895 1/20 0.41
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TYR P14679 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001409 0.87 SKP2 (0.47) SKP2SIGMAR1HPGDNPC1MAPK1
SCHEMBL9177318 0.83 SIGMAR1 (0.62) SKP2SIGMAR1IGF1RALOX15GLA
SCHEMBL7637395 0.83 CNR1 (0.45) SIGMAR1ALDH1A1
SCHEMBL19000295 0.82 ESR1 (0.46) SIGMAR1IGF1RALOX15ALDH1A1HSD17B10
SCHEMBL19000273 0.82 SIGMAR1 (0.44) SKP2SIGMAR1IGF1RALOX15ALDH1A1
SCHEMBL8641170 0.82 MEN1 (0.44) SIGMAR1HPGDMAPK1HTTALOX15
SCHEMBL30645684 0.82 MEN1 (0.44) SIGMAR1HPGDMAPK1HTTALOX15
SCHEMBL9485320 0.81 SKP2 (0.52) SKP2HPGDNPC1MAPK1HTT
SCHEMBL22252178 0.80 CTRC (0.41) SKP2SIGMAR1HPGDNPC1MAPK1
SCHEMBL5703478 0.80 SKP2 (0.47) SKP2HPGDNPC1MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed