Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645262 | 0.95 | CA1 (0.33) | CYP2C19CYP1A2APEX1RARARARB | |
| SCHEMBL18493502 | 0.95 | CYP2C19 (0.40) | CYP2C19CYP1A2APEX1RXRARXRB | |
| SCHEMBL868584 | 0.90 | CA1 (0.36) | CYP2C19CYP1A2APEX1RXRARXRB | |
| SCHEMBL30115188 | 0.90 | CA1 (0.36) | CYP2C19CYP1A2APEX1RXRARXRB | |
| SCHEMBL28445506 | 0.87 | APEX1 (0.40) | CYP2C19CYP1A2APEX1CASP3CASP6 | |
| SCHEMBL29268646 | 0.86 | RXRA (0.38) | CYP2C19CYP1A2APEX1RXRARXRB | |
| SCHEMBL7644494 | 0.86 | CYP1A2 (0.35) | CYP2C19CYP1A2APEX1RXRARXRB | |
| SCHEMBL9067857 | 0.85 | APEX1 (0.32) | APEX1RXRARXRBCASP3CASP6 | |
| SCHEMBL7642389 | 0.85 | — | — | |
| SCHEMBL18493504 | 0.85 | RXRA (0.39) | CYP2C19CYP1A2APEX1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465548-B1 | 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING | YOSHITOMI FINE CHEMICALS, LTD. (JP) | 2002-10-15 | — | — | US | disclosed |