SCHEMBL7645262

SCHEMBL7645262

CC(C)(C)c1ccc(OP(=O)(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c2ccc(-c3ccc(P(=O)(Oc4ccc(C(C)(C)C)cc4C(C)(C)C)c4ccc(-c5ccc(P(=O)(Oc6ccc(C(C)(C)C)cc6C(C)(C)C)Oc6ccc(C(C)(C)C)cc6C(C)(C)C)cc5)cc4)cc3)cc2)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CYP2C19 P33261 2/20 0.33
APEX1 P27695 1/20 0.33
CYP1A2 P05177 1/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RARG P13631 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640652 0.95 CYP2C19 (0.37) CA1CA2CA9CYP2C19APEX1
SCHEMBL868584 0.94 CA1 (0.36) CA1CA2CA9CYP2C19APEX1
SCHEMBL30115188 0.94 CA1 (0.36) CA1CA2CA9CYP2C19APEX1
SCHEMBL7642389 0.90
SCHEMBL18493502 0.89 CYP2C19 (0.40) CA1CA2CA9CYP2C19APEX1
SCHEMBL29268646 0.86 RXRA (0.38) CA1CA2CA9CYP2C19APEX1
SCHEMBL824489 0.86 KDM4E (0.32) CA1CA2CA9CYP2C19APEX1
SCHEMBL7641824 0.85 CA1 (0.31) CA1CA2CA9CYP2C19APEX1
SCHEMBL17068810 0.84 APEX1 (0.30) CA1CA2CA9CYP2C19APEX1
SCHEMBL28445506 0.83 APEX1 (0.40) CA1CA2CA9CYP2C19APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465548-B1 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-10-15 US disclosed