⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654308 | 0.78 | TSHR (0.30) | — | |
| SCHEMBL1831053 | 0.74 | — | — | |
| SCHEMBL673887 | 0.73 | — | — | |
| SCHEMBL8433008 | 0.73 | — | — | |
| SCHEMBL10426770 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL339030 | 0.71 | — | — | |
| SCHEMBL4622908 | 0.70 | — | — | |
| Butadiene SCHEMBL17686472 | 0.69 | — | — | |
| Propene SCHEMBL4734549 | 0.69 | — | — | |
| SCHEMBL6135905 | 0.69 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388020-B2 | MODIFIED WITH LESS THAN 5% BY WEIGHT OF MONOFUNCTIONAL, DIFUNCTIONAL AND POLYFUNCTIONAL MONOMERS; IMPROVED MELT PROCESSABILITY; SHEETS, FILMS, PANELS, COATINGS, PIPES, HOLLOW OBJECTS AND FOAMS | BOREALIS GMBH (AT) | 2002-05-14 | — | — | US | disclosed |
| US-20010016628-A1 | Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams | BOREALIS GMBH (AU) | 2001-08-23 | — | — | US | disclosed |