Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910806 | 0.83 | HTR6 (0.45) | HTR6SIGMAR1HTR2A | |
| SCHEMBL4652368 | 0.77 | HTR6 (0.46) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL8964848 | 0.77 | HTR6 (0.46) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL8161933 | 0.77 | HTR6 (0.49) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL8569207 | 0.77 | HTR6 (0.49) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL8568650 | 0.77 | HTR6 (0.49) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL1539037 | 0.76 | HTR6 (0.45) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL6911374 | 0.76 | HTR6 (0.49) | HTR6SIGMAR1HTR2A | |
| SCHEMBL1453509 | 0.75 | HTR6 (0.58) | HTR6SIGMAR1HTR2AKDM4ELMNA | |
| SCHEMBL6909204 | 0.74 | HTR6 (0.50) | HTR6SIGMAR1HTR2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365763-B1 | METALLOCENES CONTAINING AROMATIC PI LIGANDS, USEFUL FOR POLYMERIZING OLEFIN MONOMER STEREO SPECIFICALLY | BASELL POLYOLEFIN GMBH (DE) | 2002-04-02 | — | — | US | disclosed |