Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642166 | 1.00 | HMOX1 (0.52) | HMOX1CYP19A1CYP11B1CYP11B2FFAR1 | |
| SCHEMBL6694813 | 0.90 | CYP24A1 (0.43) | CYP24A1 | |
| SCHEMBL6699765 | 0.81 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2CYP24A1 | |
| SCHEMBL8343697 | 0.81 | FFAR1 (0.57) | FFAR1FFAR4LTA4HLTB4RLTB4R2 | |
| SCHEMBL8008297 | 0.81 | FFAR1 (0.57) | FFAR1FFAR4LTA4HLTB4RLTB4R2 | |
| SCHEMBL6699772 | 0.80 | HMOX1 (0.41) | HMOX1HRH3 | |
| SCHEMBL7638503 | 0.79 | TBXAS1 (0.42) | MAPTCYP24A1 | |
| SCHEMBL7638512 | 0.79 | TBXAS1 (0.42) | MAPTCYP24A1 | |
| SCHEMBL8014867 | 0.78 | FFAR1 (0.50) | FFAR1FFAR4LTA4HLTB4RLTB4R2 | |
| SCHEMBL6694672 | 0.78 | CYP11B1 (0.42) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | claimed |
| US-6380400-B1 | DIMETHYLTHIOCARBAMIC ACID ESTER; VIRICIDES | FEDIJ VICTOR (US) | 2002-04-30 | — | — | US | disclosed |
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |