Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368408 | 0.73 | PDE3A (0.42) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL9470349 | 0.71 | LMNA (0.39) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL17453435 | 0.70 | PDE3A (0.45) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL28767671 | 0.68 | PDE3A (0.43) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL599849 | 0.68 | PDE3A (0.46) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL599848 | 0.68 | PDE3A (0.46) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL706810 | 0.68 | PDE3A (0.41) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL9234666 | 0.68 | PDE3A (0.39) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL28829196 | 0.68 | PDE3A (0.49) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL7805953 | 0.68 | PDE3A (0.39) | PDE3ALMNACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841344-B1 | 1-(2-DEOXY-2-FLUORO-4-THIO-BETA-D-ARABINOFURANOSYL)CYTOSINES | YAMASA CORP (JP) | 2002-09-25 | — | — | EP | disclosed |