Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | POLG | P54098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234666 | 1.00 | PDE3A (0.39) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL8080057 | 0.78 | PDE3A (0.38) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL30504537 | 0.78 | ALB (0.41) | ALBPOLG | |
| SCHEMBL9470349 | 0.70 | LMNA (0.39) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL706810 | 0.69 | PDE3A (0.41) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL368408 | 0.68 | PDE3A (0.42) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL7642787 | 0.68 | PDE3A (0.40) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL28767671 | 0.67 | PDE3A (0.43) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL18016991 | 0.67 | LMNA (0.41) | PDE3ALMNACACNA1FALBMAPT | |
| SCHEMBL19605808 | 0.66 | PDE3A (0.36) | PDE3ALMNACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756595-A1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC (CA) | 1997-02-05 | — | — | EP | claimed |
| WO-1995029176-A1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1995-11-02 | — | — | WO | claimed |
| EP-1140937-A2 | ANTIVIRAL NUCLEOSIDE ANALOGUES | Shire Biochem Inc. (CA) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039143-A2 | ANTIVIRAL NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2000-07-06 | — | — | WO | disclosed |
| EP-0756595-A1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC (CA) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995029176-A1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1995-11-02 | — | — | WO | disclosed |