Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraethylene Glycol SCHEMBL11031088 | 0.87 | THRB (0.46) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Di(Hydroxyethyl)Ether SCHEMBL8961314 | 0.85 | THRB (0.44) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Di(Hydroxyethyl)Ether SCHEMBL8994648 | 0.85 | THRB (0.44) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL5053476 | 0.82 | TSHR (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL2688353 | 0.82 | LMNA (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL134219 | 0.82 | LMNA (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL5694042 | 0.82 | LMNA (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL899017 | 0.82 | LMNA (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL898587 | 0.82 | LMNA (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL2470338 | 0.82 | LMNA (0.48) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420441-B1 | DISPERSING REMOVABLE CROSSLINKED POLYMER POROGENS IN A POLYSILOXANE, CURING, AND HEATING TO REMOVE POROGEN; LOW DIELECTRIC CONSTANT; HIGH POROSITY; INSULATION MATERIALS | SHIPLEY COMPANY, L.L.C. | 2002-07-16 | — | — | US | claimed |