Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643003 | 0.86 | PLA2G2A (0.46) | CYP3A4ALDH1A1PLA2G2ABLMCNR2 | |
| SCHEMBL6326806 | 0.85 | NPC1 (0.53) | ALDH1A1TSHRPLA2G2ABLMCNR2 | |
| SCHEMBL15518329 | 0.84 | CNR2 (0.48) | PLA2G2ABLMCNR2ICMTALB | |
| SCHEMBL3982113 | 0.84 | NPC1 (0.55) | ALDH1A1PLA2G2ABLMCNR2NPC1 | |
| SCHEMBL4744062 | 0.84 | NPC1 (0.55) | ALDH1A1PLA2G2ABLMCNR2NPC1 | |
| SCHEMBL10951817 | 0.84 | NPC1 (0.55) | ALDH1A1PLA2G2ABLMCNR2NPC1 | |
| SCHEMBL10956818 | 0.84 | NPC1 (0.55) | ALDH1A1PLA2G2ABLMCNR2NPC1 | |
| SCHEMBL10952007 | 0.84 | NPC1 (0.55) | ALDH1A1PLA2G2ABLMCNR2NPC1 | |
| SCHEMBL45791 | 0.83 | CYP3A4 (0.59) | CYP3A4ALDH1A1TSHRPSMD14MAPK1 | |
| SCHEMBL11667468 | 0.82 | CNR2 (0.50) | PLA2G2ABLMCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |