Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879272 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL3889184 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL9580447 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL9580445 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL9515253 | 0.86 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL3951825 | 0.83 | SLC6A3 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL14300482 | 0.83 | SLC6A3 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL19749365 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL19262111 | 0.79 | HTR2C (0.63) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL16585369 | 0.79 | HTR2C (0.63) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061318-B1 | PROCESS FOR THE SYNTHESIS OF (+) AND (-) -1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE | DOV PHARMACEUTICAL INC (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2343286-A1 | Dibenzo[b,f][1,4]oxazepine derivatives as inhibitors of histone deacetylase | Methylgene, Inc. (CA) | 2011-07-13 | — | — | EP | disclosed |