Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879272 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL9580447 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL9580445 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL764313 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL3889184 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL1507359 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3246125 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7026793 | 0.80 | HTR2C (0.59) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL14300482 | 0.80 | SLC6A3 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL3951825 | 0.80 | SLC6A3 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |