Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193916 | 0.84 | ALDH1A1 (0.46) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| SCHEMBL1792016 | 0.84 | ALDH1A1 (0.46) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL250009 | 0.81 | ALDH1A1 (0.43) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| Ammonia Solution, Strong SCHEMBL28873134 | 0.81 | ALDH1A1 (0.43) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| Ammonia Solution, Strong SCHEMBL28763213 | 0.81 | ALDH1A1 (0.43) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| Water SCHEMBL8817645 | 0.81 | ALDH1A1 (0.43) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| SCHEMBL9703223 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1KDM4ECYP3A4 | |
| SCHEMBL11337630 | 0.79 | HTR3E (0.47) | TSHRALDH1A1MAPTLMNANPC1 | |
| SCHEMBL20670455 | 0.79 | ALDH1A1 (0.64) | TSHRCYP1A2ALDH1A1MAPTTDP1 | |
| SCHEMBL21788097 | 0.79 | ALDH1A1 (0.64) | TSHRCYP1A2ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115926156-B | Preparation method of color-changing polyurea | 青岛爱尔家佳新材料股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-115926156-A | Preparation method of color-changing polyurea | 青岛爱尔家佳新材料股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-6465693-B2 | TRANSITION METAL CATALYZED ARYLATION OR VINYLATION; COMBINATORIAL CHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-10-15 | — | — | US | disclosed |
| US-20010031894-A1 | Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates | BUCHWALD STEPHEN L (US) | 2001-10-18 | — | — | US | disclosed |
| US-6235936-B1 | TRANSITION METAL CATALYST FOR ARYLATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |
| EP-1058678-A2 | METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES | Massachusetts Institute of Technology (US) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999043643-A2 | METAL-CATALYZED ARYLATIONS AND VINYLATIONS OF HYDRAZINES, HYDRAZONES, HYDROXYLAMINES AND OXIMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031894-A1 | Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates | IDO1, IDO2, AHR | TSHR 2375/4885CYP1A2 43/4885ALDH1A1 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.