SCHEMBL7643256

SCHEMBL7643256

O=C(O)C1C2C=CC(CC2)C1C(=O)OCCO

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.59
APEX1 P27695 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 2/20 0.47
PPM1B O75688 2/20 0.41
PTPN1 P18031 2/20 0.41
PPP1CC P36873 2/20 0.41
KDM4E B2RXH2 2/20 0.40
EGLN1 Q9GZT9 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
MAPT P10636 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648156 0.90 POLB (0.55) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL7647029 0.90 ALDH1A1 (0.62) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL11515674 0.82 ALDH1A1 (0.51) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL23626950 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL19387861 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL16728379 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL11247130 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL22623107 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL22579811 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2
SCHEMBL30760583 0.81 POLB (0.61) POLBAPEX1TDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6387589-B1 COPOLYMER; SEMICONDUCTOR HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-05-14 US claimed
US-6368771-B1 COPOLYMERS; SEMICONDUCTORS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-09 US claimed
US-6387589-B1 COPOLYMER; SEMICONDUCTOR HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-05-14 US disclosed
US-6368771-B1 COPOLYMERS; SEMICONDUCTORS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-09 US disclosed