SCHEMBL7643272

SCHEMBL7643272

C[SiH](C)[Zr](Cl)(Cl)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
PGR P06401 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
BCHE P06276 2/20 0.32
ACHE P22303 1/20 0.32
SRD5A2 P31213 1/20 0.32
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3384917 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL618217 0.81 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7037927 0.80 PNMT (0.43) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30536713 0.78 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7602119 0.78 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL1131322 0.74 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3384059 0.74 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3385391 0.74 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7878851 0.74 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3385667 0.74 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0855413-B1 Ethylene copolymer rubber composition JSR CORP (JP) 2002-01-02 EP disclosed
US-5914372-A VULCANIZABLE RUBBER CONSISTS OF A COPOLYMER OF ETHYLENE-ALPHA-OLEFIN-NON-CONJUGATED DIENE, ATLEAST ONE VULCANIZING AGENT, AND A PEROXY CROOSLINKING AGENT JSR CORPORATION (JP) 1999-06-22 US disclosed
EP-0855413-A1 Ethylene copolymer rubber composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-07-29 EP disclosed