Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 3/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643520 | 1.00 | LAP3 (0.52) | LAP3SLC7A5CA12CA1CA2 | |
| SCHEMBL28434433 | 0.78 | — | — | |
| SCHEMBL28434436 | 0.78 | — | — | |
| SCHEMBL30547467 | 0.77 | SLC7A5 (0.46) | LAP3SLC7A5ANPEPERAP1DPP4 | |
| SCHEMBL2990208 | 0.75 | MMP2 (0.42) | LAP3CA12CA1CA2MMP1 | |
| Valine SCHEMBL29415345 | 0.74 | SLC7A5 (0.79) | LAP3SLC7A5ANPEP | |
| Valine SCHEMBL1758770 | 0.74 | SLC7A5 (0.79) | LAP3SLC7A5ANPEP | |
| Valine SCHEMBL16010343 | 0.74 | SLC7A5 (0.79) | LAP3SLC7A5ANPEP | |
| Valine SCHEMBL1758768 | 0.74 | SLC7A5 (0.79) | LAP3SLC7A5ANPEP | |
| SCHEMBL8383247 | 0.74 | MMP2 (0.46) | LAP3CA12CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465189-B1 | PARTITIONING AND REPLICATING INCREASED AFFINITY BLENDED NUCLEIC ACIDS; DEVELOPMENT OF ELASTASE INHIBITORS; MEDICAL DIAGNOSIS OF RESPIRATORY SYSTEM, GENETIC, AND RHEUMATIC DISORDERS | GILEAD SCIENCES, INC. | 2002-10-15 | — | — | US | disclosed |