Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448497 | 1.00 | MAPK1 (0.35) | MAPK1GRIN1GRIN2AGRIN2BPDE10A | |
| SCHEMBL7643559 | 1.00 | MAPK1 (0.35) | MAPK1GRIN1GRIN2AGRIN2BPDE10A | |
| SCHEMBL2786806 | 0.87 | FPR2 (0.34) | — | |
| Clothianidine SCHEMBL237824 | 0.87 | RECQL (0.39) | LMNARECQLALDH1A1MAPTPKM | |
| Clothianidine SCHEMBL14273626 | 0.87 | RECQL (0.39) | LMNARECQLALDH1A1MAPTPKM | |
| Clothianidine SCHEMBL2413061 | 0.87 | RECQL (0.39) | LMNARECQLALDH1A1MAPTPKM | |
| Clothianidine SCHEMBL21214 | 0.87 | RECQL (0.39) | LMNARECQLALDH1A1MAPTPKM | |
| SCHEMBL237828 | 0.87 | FPR2 (0.34) | — | |
| SCHEMBL237829 | 0.87 | FPR2 (0.34) | — | |
| SCHEMBL237130 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140350-A | APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | claimed |
| US-20170071203-A1 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| US-9549552-B2 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2017-01-24 | — | — | US | disclosed |
| US-20160058002-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-03-03 | — | — | US | disclosed |
| US-20150272931-A1 | New Treatment | NOVARTIS CENTRE DE RECHERCHE SANTE ANIMALE SA (CH) | 2015-10-01 | — | — | US | disclosed |
| US-20080287425-A1 | Method for Controlling Chinch Bugs | FMC CORPORATION (US) | 2008-11-20 | — | — | US | disclosed |
| US-6403058-B1 | CONTROLLING TERMITES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |
| US-6391327-B1 | SYNERGISTIC PESTICIDAL COMPOSITION COMPRISING PRALLETHRIN AND NEONICOTINOID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6284782-B1 | INSECTICIDES; SYNERGISTIC MIXTURES | SUMITOMO CHEMICAL CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |
| US-6255340-B1 | SYNERGISTIC MIXTURE OF PRALLETHRIN AND A NEONICOTINOID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-03 | — | — | US | disclosed |
| US-6201017-B1 | TOPICALLY APPLYING TO ANIMAL A LIQUID MIXTURE COMPRISING 1-(TETRAHYDRUFURAN-3-YL)METHYL-3-METHYL-2-NITROGUANIDINE, A GLYCOL OR ITS MONOALKYL ETHER AND A SOLVENT TO CONTROL FLEAS, LICE, TICKS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6140350-A | APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0976328-A2 | Ectoparasite controlling agent for animals | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0966961-A1 | Method for controlling ectoparasites | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170071203-A1 | Active compound combinations having insecticidal properties | ACHE, BCHE, DDT | MAPK1 3795/4885GRIN1 1299/4885GRIN2A 2417/4885 |
| US-20150272931-A1 | New Treatment | NISCH, TYR, DDT | MAPK1 3727/4885GRIN1 2749/4885GRIN2A 2056/4885 |
| US-20080287425-A1 | Method for Controlling Chinch Bugs | NISCH, NIT2, COX6C | MAPK1 4219/4885GRIN1 4567/4885GRIN2A 4106/4885 |
| US-20160058002-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL PROPERTIES | DDT, ACHE, TIAL1 | MAPK1 3961/4885GRIN1 906/4885GRIN2A 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.