Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965847 | 0.92 | PRKCA (0.47) | PRKCAGLS2FAAHCNR1CNR2 | |
| SCHEMBL8669152 | 0.87 | PRKCA (0.47) | PRKCAGLS2ALDH1A1PRKCDCA1 | |
| SCHEMBL125718 | 0.83 | PRKCA (0.50) | PRKCAGLS2ALDH1A1PRKCDCA1 | |
| SCHEMBL7520665 | 0.83 | PRKCA (0.50) | PRKCAGLS2ALDH1A1PRKCDCA1 | |
| SCHEMBL4834768 | 0.83 | CTSK (0.50) | PRKCAGLS2ALDH1A1PRKCDCA1 | |
| SCHEMBL7518686 | 0.83 | PRKCA (0.50) | PRKCAGLS2ALDH1A1PRKCDCA1 | |
| SCHEMBL20512292 | 0.83 | PRKCA (0.49) | PRKCAGLS2ALDH1A1FAAHCA1 | |
| SCHEMBL31504088 | 0.82 | PRKCA (0.51) | PRKCAGLS2FAAHCA2 | |
| SCHEMBL2959330 | 0.82 | PRKCA (0.56) | PRKCAGLS2ALDH1A1FAAHPRKCD | |
| SCHEMBL27820706 | 0.82 | PRKCA (0.51) | PRKCAGLS2FAAHCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325169-B1 | LISOFYLLINE ANALOGUES AND THEIR PHARMEACUETICAL USES | Univ Virginia Patent Found (US) | 2015-10-07 | — | — | EP | disclosed |
| EP-2325169-A9 | LISOFYLLINE ANALOGUES AND THEIR PHARMEACUETICAL USES | University Of Virginia Patent Foundation (US) | 2012-03-21 | — | — | EP | disclosed |